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The Methylation Function Test
Stop guessing what your body needs. This test decodes your unique genetic variants in pathways that control energy production, mental clarity, and your body's natural detoxification. It translates complex DNA science into a clear, actionable plan for your diet, supplements, and lifestyle—so you can move from feeling okay to feeling your best.
CompareMedsRx Exclusive Price
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What's Included
Most tests leave you guessing. We give you expert answers.With CompareMedsRx, you'll get:
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30 Min. Pre-Test Session$100$250Meet with a genetic counselor before your test to talk through how you’re feeling day to day, your symptoms, lifestyle, and health history. You’ll share what feels “off,” what you’re worried about, and what you’d like to improve—whether that’s energy, mood, focus, sleep, or long-term wellness—so your methylation testing is tailored to your personal goals and gives you clear, actionable insights, not just lab numbers. |
30 Min. Post-Test Session$100$250Your genetic counselor will walk you through your methylation results in clear, simple language—what’s working well, where there may be bottlenecks, and how this may relate to your energy, mood, detox, and overall wellness. Together, you’ll explore practical ways to support your methylation through food, targeted supplements, and daily habits, so you leave with a clear, personalized plan you can start using right away for maximum benefit. |
Key Features
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What's Methylation, and Why Take a Test?
Methylation is a key process that helps your body convert nutrients into energy, support brain function, detoxification, and cell repair.
Your genes influence how efficiently this process works and understanding your methylation profile can help you better support long-term health and healthy aging.
◦ This test is available for ages 13+ (with a guardian account if under 18).
◦ This test is not intended to diagnose, treat, cure, or prevent any disease and should not be considered a substitute for professional medical advice.
What's Methylation, and Why Take a Test?
Methylation is a key process that helps your body convert nutrients into energy, support brain function, detoxification, and cell repair.
Your genes influence how efficiently this process works and understanding your methylation profile can help you better support long-term health and healthy aging.
Discover if you have any genetic variants that affect how your body uses vitamins and nutrients in methylation.
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Why Pay Our Price of $800?
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Anna Schon, MS, CGC
Anna is a board-certified genetic counselor with a background in neurology, rare disease, and other hereditary conditions. She holds an MS in Genetic Counseling from Sarah Lawrence College. Anna combines her expertise in genomics, and longevity science to help patients personalize their health strategies. Anna uses genetic insights to guide sustainable weight management and support long-term wellness.
David Sharpe, MS, CGC
David is a board-certified genetic counselor with over 14 years of experience and is a graduate of the Genetic Counseling program from Sarah Lawrence College. He specializes in using genetic tools to support and improve health outcomes. David is passionate about equitable, compassionate care and helps patients make informed, confident choices for lasting wellness.
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1. Order Your Kit, Schedule a Pre-Test Counseling Session, & Answer Questionnaire
After purchase, you’ll receive a payment confirmation, session reminders, and a link as your pre-test counseling approaches.
2. Receive & Register Your DNA Kit
Your kit arrives in 3 days. Register it, complete your swab, and mail it back. You’ll receive a confirmation once it reaches the lab.
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3. Get Results & Review in Post-Test Session
Get your results 3 weeks after your sample reaches the lab along with a link to schedule your post-test session with a nutritionist.
4. Thrive & Optimize
Confidently implement your tailored recommendations, supported by our resources, to enhance your daily well-being.
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45 Min. Weight Management Counseling Session
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The Methylation Function Test Kit
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45 Min. Methylation Function Counseling Session
Why Bundle?
- Holistic Health Insights
- Personalized Action Plans
- Save +$700 on regular kit and processing fees
Results are typically available within 2–3 weeks after your sample reaches the lab. You’ll receive a detailed, easy-to-understand report with personalized recommendations. The total turn-around-time from order placement to delivery of results to the customer is 3- 4 weeks and depends on how quickly the saliva sample is returned to the lab.
Here is the step by step time line:
- Test payment
- Physician orders test
- 2-3 days post order US Biotek ships kit to consumer
- Consumer returns sample within 1 week of kit receipt
- Lab receives kit 2-4 days post kit shipment
- Test results are available 2 weeks post sample receipt
This test is great for anyone looking to:
- Understand their nutrient needs
- Support mood, energy, or detoxification
- Optimize their wellness through personalized nutrition
- Address family history of inflammation, heart issues, or fatigue.
- Explore root causes of symptoms like brain fog or sluggishness
Each gene result is assigned a priority level:
Low Priority – No major concerns; your body is likely processing nutrients normally in this area.
Medium Priority – There may be a slight need for extra nutritional support.
High Priority – Your genetic variant may significantly affect methylation or detox, so targeted support may be helpful.
These are not medical risk levels, but rather guidance for where to focus nutrition and wellness attention.
When you order the bundle through CompareMedsRx you receive:
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The Methylation Function Test
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One session with a licensed genetic counselor to explain your results
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One session with a nutritionist to help you apply the insights to your daily life
This combination helps you turn results into a personalized action plan.
Whole foods don’t contain 5-MTHF in its supplement form but do contain natural folate, which people without MTHFR variants can typically convert into 5-MTHF.
Best food sources of natural folate:
- Dark leafy greens (spinach, kale, Swiss chard, romaine lettuce)
- Asparagus
- Avocados
- Brussels sprouts
- Broccoli
- Lentils, black beans, pinto beans
- Beets
- Oranges and citrus fruits
If you have an MTHFR variant, your body may not efficiently convert this food folate into 5-MTHF. That’s why supplemental L-methylfolate is often recommended.
Fortified Foods contain synthetic Folic Acid.
Examples: cereal, bread, energy bars
These typically contain folic acid, which may not be well-processed by people with MTHFR gene variants. These are not reliable sources of 5-MTHF for individuals with impaired methylation.
Dietary supplements are sources of methylated folate. These provide 5-MTHF in a highly bioavailable, ready-to-use form:
- L-methylfolate (also labeled as Metafolin® or Quatrefolic®)
- Common doses: 400 mcg – 1,000 mcg (sometimes higher under medical guidance)
- Often found in:
- Methylated B-complex formulas
- Prenatal vitamins (premium brands)
- MTHFR-targeted supplements
Note: Always check the label to make sure it says “L-methylfolate,” or “5-MTHF,”—not just "folic acid" or "folate."